(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate - Names and Identifiers
Name | Disodium folinate
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Synonyms | CL143 Disodium folinate Disodium levofolinate Levoleucovorin disodium (2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid disodium salt
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CAS | 163254-40-8
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InChI | InChI=1/C20H23N7O7.2Na/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);;/q;2*+1/p-2/t12-,13-;;/m0../s1 |
(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate - Physico-chemical Properties
Molecular Formula | C20H21N7Na2O7
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Molar Mass | 517.13 |
Storage Condition | Sealed in dry,Room Temperature |
(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate - Introduction
Diodium folinate, chemical formula C19H17N7Na2O6S, is a hydrochloric acid form of folinic acid, also known as sodium folate. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
- Disodium folinate is a colorless crystal, soluble in water and a few organic solvents.
-Its solution is weakly alkaline.
- Disodium folinate is stable in the air, but it is easy to decompose under light.
Use:
-diodium folinate is an important vitamin B9 supplement that is widely used in food, medicine and cosmetics.
-It can be used to prevent and treat diseases related to folic acid deficiency, such as megaloblastic anemia.
- Disodium folinate is also used in the synthesis of certain adjuvant or chemotherapeutic drugs.
Method:
- Disodium folinate can be prepared by synthetic or biological fermentation methods.
-The synthesis method is generally through the synthesis of folic acid (dihydrofolic acid) intermediates, and then reacted with alkali to form Disodium folinate.
-The biological fermentation method can use certain bacteria or yeasts to produce folinic acid, and then purify and sodium reaction to obtain Disodium folinate.
Safety Information:
- Disodium folinate is generally safe under normal use, but excessive intake may cause folinic acid poisoning.
-for individual groups such as pregnant women, lactating women, individuals under certain drug treatment, etc., need to follow the doctor's advice.
-During storage, avoid contact with organic substances and strong oxidants to prevent their degradation.
Please note that before using any chemical substances, it is recommended to learn more about the relevant safe use precautions and follow the correct operating procedures.
Last Update:2024-04-09 15:17:53